Nolvadex is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Nolvadex reduces levels of estrogen: Rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.

The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction in IGF-1 (individuals using anabolic steroids were not studied though) from use of Nolvadex.

The fact that Nolvadex will reduce water retention may result in the user agreeing that gains are less, since weight gain is less, thus reinforcing the bias.,


Application:

Many women have breast cancer that tests positive for estrogen receptors (ER+). This means that estrogen promotes the growth of thebreast cancer cells. Tam0xifen blocks the effects of estrogen on these cells. It is often called an "anti-estrogen."

Tam0xifen slows or stops the growth of cancer cells that are already present in the body. It helps keep the original breast cancer from coming back and helps prevent new cancer in the opposite breast. It also reduces the risk of breast cancer in women who have a high risk for this disease.

Tam0xifen can be used to decrease the rate of bone maturation and alter the predicted adult height, which is usually lower in those with premature puberty. This medication has been shown to be affective for both boys and girls. It was observed that there was persistent retardation of longitudinal and cortical radical bone growth, which then led to come concern about the use of tam0xifen in young humans.

Tam0xifen can be used in conjunction with other medications  to form a treatment regime to regulate the growth of new blood vessels.

COA: